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What is the Role of CV Screening Tests in Medicine and Legislation? (28 Feb 2011)

Three papers in Archives of Internal Medicine scrutinize the role of cardiovascular screening tests not only in medicine but in legislation. In the first article, Nicholas Wald and Joan Morris introduce a new interactive tool that determines the detection and false-positive rates of screening tests. The authors illustrate the value of the tool with the examples…

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FDA Approves Azilsartan Medoxomil (Edarbi) for High Blood Pressure (25 Feb 2011)

The FDA has approved azilsartan medoxomil (Edarbi, Takeda) for the treatment of high blood pressure. The new angiotensin II receptor blocker (ARB) will be available in 80 mg and 40 mg doses. The recommended dose is 80 mg once daily. The 40 mg dose is used in combination with a diuretic. The FDA said that, in clinical…

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Study Probes BMI-Associated Risk in Asia (24 Feb 2011)

The association between BMI and the risk of death in Asia is mostly similar to that seen in people of European origin, but there may be some important differences between populations, suggesting that being underweight may be a more potent risk factor than being overweight in Asia. In a large pooled analysis including more than…

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Air Pollution and Cocaine Among MI Triggers Analyzed in Lancet Study (23 Feb 2011)

Air pollution is a weak cause of MI, increasing risk by only 5%, but because so many people are exposed to polluted air the population effect is quite large. By contrast, cocaine increases MI risk by 23 times, but does not have nearly as large an effect on the population. These are two of the…

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High Pacemaker Insertion Rate Observed After CoreValve TAVI Implantation (23 Feb 2011)

One-third of patients who underwent transcatheter aortic valve implantation with the CoreValve device required a permanent pacemaker within 30 days, according to a report published online in Circulation. Researchers in the UK examined data from 243 patients who received the CoreValve device. The incidence of LBBB was 13% prior to the procedure and 61% afterward. Patients…

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Study Finds Nitroglycerin Improves Bone Density (22 Feb 2011)

A new study raises hope that nitroglycerin may help stem the rising tide of fractures in the elderly. Earlier research with nitrates had suggested the possibility of benefit in this area. Now, in a paper published in JAMA, Sophie Jamal and colleagues report the result of a single-center, double-blind, placebo-controlled trial of 243 postmenopausal women randomized…

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Study Links Stent Thrombosis to Circadian Variation (22 Feb 2011)

Circadian patterns have long been known to influence the cardiovascular system, resulting in early morning peaks in blood pressure, heart rate, and certain hormone levels, as well as an increased risk for MI and sudden cardiac death. Now, in a study published in JACC: Cardiovascular Interventions, Karim Mahmoud and colleagues have found that coronary stent…

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Quarter of U.S. Adults 45 and Older Taking Statins (17 Feb 2011)

One-quarter of U.S. adults age 45 and older are taking statins, and one-half of men ages 65 to 74 are taking these drugs, according to the CDC’s annual report on trends in health statistics. From 1988 to 1994, only 2% of adults age 45 and older were taking statins. High cholesterol levels have been declining, according to…

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Study Sheds Light on Racial Disparities in Hospital Readmissions (15 Feb 2011)

Although many studies in recent years have explored the issue of racial disparities in health care, a new study scrutinizes the effect of race on hospital readmissions, an area that has not been previously examined. In a report appearing in JAMA, Karen Joynt and colleagues examined Medicare data to study readmissions after hospitalizations for acute…

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AHA Releases Updated Guidelines for the Prevention of CV Disease in Women (15 Feb 2011)

Newly published online in Circulation, updated AHA guidelines for the prevention of cardiovascular disease in women emphasize practical medical advice. “These recommendations underscore the fact that benefits of preventive measures seen day-to-day in doctors’ offices often fall short of those reported for patients in research settings,” said Lori Mosca, chair of the guidelines writing committee, in…

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