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Adiposity and Natriuretic Peptides: Where Does the Fat Go? (24 Apr 2013)

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Ian Neeland, MD

In a study recently published online by JACC, investigators assess the association between natriuretic peptide levels and body-fat distribution. Ian Neeland, the lead author of the study, responds to John Ryan’s questions.

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Cuban History Offers Important Lessons For Global Health Today (11 Apr 2013)

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A large new study from Cuba shows the impressive benefits that can be achieved with weight loss and increased exercise. Much more ominously, the same study shows the dangers associated with weight gain and less exercise. In the study, published in BMJ, researchers took advantage of a “natural” experiment that occurred in Cuba as a result of a…

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Should Body Weight Influence Choice of Antihypertensive Therapy? (7 Dec 2012)

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The hypertension field has been troubled by repeated observations that normal weight patients have more cardiovascular (CV) events than obese patients. Now a new analysis of a large hypertension trial confirms this finding but also suggests that it may be explained by either an adverse effect of diuretics or a protective effect of calcium-channel blockers in non-obese…

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The Role of Social Media in Fighting Childhood Obesity (3 Dec 2012)

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“More parental involvement and more interaction with counselors and peers was associated with greater success rates for overweight children and teens who participated in an online intervention.”

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NIH Trial of Lifestyle Intervention for Type 2 Diabetes Stopped for Futility After 11 Years (22 Oct 2012)

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The NIH today announced the early termination of a large randomized trial testing a lifestyle intervention approach to weight loss in type 2 diabetics. More than 5,000 patients with type 2 diabetes were randomized to participate in an intensive lifestyle intervention program or a traditional program of diabetes support and education in Look AHEAD (Action for…

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A Manhattan Project to End the Obesity Epidemic (13 Sep 2012)

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A newly launched nonprofit organization, the Nutrition Science Initiative, will try to find an answer to the question,  “What should we eat to be healthy?” Called NuSI (pronounced “new see”) for short, the organization is nothing if not ambitious: its goal is to seek “the end of fad diets and high obesity rates.” NuSI’s founders are Gary Taubes and Peter Attia. Taubes…

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FDA Approves Another New Weight Loss Drug (18 Jul 2012)

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The US FDA approved on Tuesday a new weight loss drug that will be called Qsymia, the brand name for the combination of two previously approved drugs, phentermine and extended-release topiramate. The drug is manufactured by Vivus, Inc. In a press release, the FDA said Qsymia had been approved for use in obese adults (BMI of 30…

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AHA and ADA Cautiously Endorse Non-Nutritive Sweeteners (9 Jul 2012)

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In a newly released scientific statement, the American Heart Association and the American Diabetes Association offer a cautious endorsement of the use of non-nutritive sweeteners in the diet. But the statement notes that the products are not “magic bullets” and that there is no strong evidence demonstrating their beneficial effects. Sugar in the diet has been…

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Subway Meals Get American Heart Association Endorsement (5 Jun 2012)

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The American Heart Association (AHA) announced yesterday that it had initiated a new program to help people choose healthy meals at restaurants. The Subway restaurant chain will be the first to display the Heart-Check Meal Certification logo next to certain selected meals. In a press release the AHA’s president, Gordon Tomaselli said the program would make “it…

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FDA Advisory Panel Recommends Approval for Weight Loss Drug Lorcaserin (10 May 2012)

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The FDA’s Endocrinologic and Metabolic Drugs Advisory Committee voted to recommend approval of lorcaserin (Lorqess, Arena). The vote was 18 in favor of approval, 4 against, and 1 abstention.