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Selections from Richard Lehman’s Literature Review: June 23rd (23 Jun 2014)

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Richard Lehman, BM, BCh, MRCGP

This week’s topics include thrombolysis for pulmonary embolism, the effect of screening and lifestyle counseling on the incidence of ischemic heart disease in the general population, and more.

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A Meta-Look at Thrombolysis vs. Conventional Anticoagulation for PE (17 Jun 2014)

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Jay Giri, MD, MPH and Saurav Chatterjee, MD

Jay Giri and Saurav Chatterjee discuss their meta-analysis of trials comparing thrombolytic therapy and conventional anticoagulation in patients at intermediate risk for pulmonary embolism.

Avatar of Larry Husten, PHD

Mixed Results for Thrombolysis in Pulmonary Embolism (17 Jun 2014)

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  The role of thrombolytic therapy for the treatment of pulmonary embolism has been unclear, as it has been difficult to measure the precise balance between enhanced clot-dissolving efficacy and greater bleeding risk produced by thrombolysis when compared with conventional anticoagulation. A new meta-analysis published in JAMA analyzed data from 16 randomized trials including 2115 patients….

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Avatar of Richard Lehman, BM, BCh, MRCGP

Selections from Richard Lehman’s Literature Review: April 28th (28 Apr 2014)

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Richard Lehman, BM, BCh, MRCGP

This week’s topics include BP targets during septic shock, reducing time-to-needle times in acute ischemic stroke, and an increase in fat and calorie consumption in U.S. statin users.

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Selections from Richard Lehman’s Literature Review: August 19th (19 Aug 2013)

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Richard Lehman, BM, BCh, MRCGP

This week’s topics include treating to risk, not to target; perceived job insecurity as a risk factor for incident CHD; ischemic preconditioning in patients undergoing CABG, and more.

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Thrombolysis Instead of Primary PCI (30 Nov 2011)

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Rita F Redberg, MD, MSc

The latest analysis of 2009 CMS data for 13,776 STEMI patients of door-in to door-out (DIDO) time by Herrin and colleagues does not bring encouraging news. After many years of hard work to reduce DIDO time for patients who present at facilities without primary PCI capability, only a small fraction of patients (<10%) are transferred…

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Long Transfer Delays for STEMI Patients at Most Hospitals Without Primary PCI (28 Nov 2011)

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Fewer than 10% of STEMI patients eligible for PCI who arrive at a hospital without PCI capability are transferred within the recommended times, according to a new study published in the Archives of Internal Medicine. Although dramatic improvements in door-to-balloon times have been achieved in recent years in PCI-capable hospitals, the new report suggests that…

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