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Avatar of Larry Husten, PHD

FDA Approves Second-Generation Heart Valve from Edwards Lifesciences (17 Jun 2014)

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The next phase of the burgeoning and rapidly maturing transcatheter aortic valve replacement (TAVR) market has begun. Edwards Lifesciences announced on Monday afternoon that the FDA had approved its second-generation Sapien XT TAVR device  for the treatment of high-risk and inoperable patients suffering from severe symptomatic aortic stenosis (AS). The Sapien XT is the successor to the first-generation Sapien device,…

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Avatar of Larry Husten, PHD

Wide Range of Radiation Dose in Children Undergoing Cardiac Procedures (9 Jun 2014)

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Children with heart disease are at increased risk for developing cancer later in life due to their exposure to radiation during imaging procedures. Since an ever-growing number of children with heart disease now reach adulthood, this may become an increasingly important public health issue. A new study published in Circulation offers some reassurance in finding…

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Avatar of Richard A. Lange, MD, MBA

Transcatheter Mitral Valve Programs: No Volume Data (4 Jun 2014)

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Richard A. Lange, MD, MBA and L. David Hillis, MD

The Society for Cardiac Angiography and Interventions (SCAI), the American Association for Thoracic Surgery (AATS), the American College of Cardiology (ACC), and the Society of Thoracic Surgeons (STS) recently joined together to provide recommendations for institutions that are considering starting and/or maintaining a transcatheter mitral valve (MV) program. Unlike PCI, for which abundant data show…

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Avatar of Harlan M. Krumholz, MD, SM

Choosing a Prosthetic Valve: What Do You Say to Your Patient? (27 May 2014)

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Harlan M. Krumholz, MD, SM

In this scenario based on prosthetic valve choice, Harlan Krumholz asks, “What do you say to your patient?”

Avatar of Larry Husten, PHD

CoreValve Availability In U.S. Threatened By Court Decision (15 Apr 2014)

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A legal injunction may severely limit the availability in the United States of Medtronic’s CoreValve device, which only received FDA approval earlier this year. The device received abundant praise recently when a large clinical trial demonstrated substantial advantages for CoreValve over traditional open-heart surgery. The injunction is the latest episode in an ongoing patent war in which Edwards Lifesciences, which pioneered…

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Avatar of Larry Husten, PHD

Survival Advantage for TAVR Over Surgery in High-Risk Patients (29 Mar 2014)

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Transcatheter aortic valve replacement (TAVR), which has been slowly and cautiously entering the clinical arena, will probably get a big boost from a new trial showing a significant mortality advtange for TAVR over traditional surgery. Results from the U.S. CoreValve High-Risk Study were presented at the American College of Cardiology in Washington, DC, and published…

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Avatar of Larry Husten, PHD

ACC.14 Preview: Renal Denervation, TAVR Comparisons, and More (24 Mar 2014)

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The ACC begins this Saturday in Washington, DC. Here’s a preview of some of the most highly anticipated late-breaking clinical trials: On Saturday morning at the opening session the world will finally learn more about the failure of Symplicity HTN-3, the Medtronic trial of renal denervation. Until recently, renal denervation was thought to be an…

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rAAA Patients More Likely to Get Surgery and Survive in the U.S. Than in England (13 Mar 2014)

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Patients with a ruptured abdominal aortic aneurysm (rAAA) have better outcomes in the United States than in England according to a new study published in the Lancet. Researchers at the University of London compared hospital data from 11,799 rAAA patients in England with 23,838 rAAA patients in the U.S. They found that U.S. patients were more likely…

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Achieving Consensus for the 2014 ACC/AHA Valvular Heart Disease Guideline (13 Mar 2014)

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Catherine M. Otto, MD and Rick Akira Nishimura, MD

The writing committee co-chairs of the 2014 ACC/AHA Valvular Heart Disease Guideline discuss how the committee achieved consensus on the future treatment of valvular disease.

Avatar of Larry Husten, PHD

French Surgeons Perform First Totally Endoscopic Aortic Valve Replacement (11 Mar 2014)

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Surgeons in France report that they have performed the first totally endoscopic aortic valve replacement (TEAVR) in two human patients. Their paper has been published in the the Journal of Thoracic and Cardiovascular Surgery. The new procedure may enable surgeons to replace the aortic valve without opening the chest, though it will still require cardiopulmonary bypass and…

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