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Avatar of Harlan M. Krumholz, MD, SM

Poor Retention of Guideline Recommendations (14 Jul 2014)

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Harlan M. Krumholz, MD, SM

Harlan Krumholz discusses a JAMA study that found a substantial proportion of Class I guideline recommendations were not durable over a 10-year period.

Avatar of Richard Lehman, BM, BCh, MRCGP

Selections from Richard Lehman’s Literature Review: July 14th (14 Jul 2014)

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Richard Lehman, BM, BCh, MRCGP

This week’s topics are leucocyte telomere length and the risk for CVD, and the association between alcohol and CVD.

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Should Doctors Be Paid Overtime for Taking Call? (10 Jul 2014)

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David Mann, MD

On call is the worst thing about being a doctor, and here’s why.

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USPSTF Finalizes Recommendations on Carotid Artery Stenosis Screening (8 Jul 2014)

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The U.S. Preventive Services Task Force has recommended against screening for asymptomatic carotid artery stenosis in the general adult population (grade D recommendation). Published in the Annals of Internal Medicine, the statement reiterates the group’s 2007 guidance. The harms of screening outweigh the benefits, the task force says. The groups notes that all screening strategies…

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Statins Are a Mess: We Need Better Data, and Shared Decision Making (7 Jul 2014)

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Ben Goldacre, MB, BS, BA, MA, MBBS, MSc

The following open letter was originally published on The British Medical Journal‘s editorial page regarding the adverse effects of statins for patients with low risk of cardiovascular disease. It was written in response to an analysis by Abramson et al, and more information on the subject can be found here. I have two observations to…

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Avatar of Richard Lehman, BM, BCh, MRCGP

Selections from Richard Lehman’s Literature Review: July 7th (7 Jul 2014)

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Richard Lehman, BM, BCh, MRCGP

This week’s topics include the effect of patients’ risks and preferences on health gains with plasma glucose level lowering in type 2 diabetes, a meta-analysis of revascularization vs. medical treatment in patients with stable CAD, and more.

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Retraction Dissolves Credibility of Acid-Bath-Generated Stem Cells (3 Jul 2014)

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Sadly, what seemed too good to be true now is: subjecting adult cells to an acid bath does not transform them into pluripotent stem cells, and the Nature papers reporting the effect have been retracted. After initial excitement over the findings in January, a number of laboratories reported having trouble duplicating the results. Then in…

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Avatar of Larry Husten, PHD

Sitagliptin Associated with Increase in Heart Failure Hospitalizations (3 Jul 2014)

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The cardiovascular effects of drugs used for glucose control in patients with diabetes have been a subject of controversy for many years now. More recently, attention has started to focus specifically on the risk for heart failure (HF). Now, an observational study will likely raise new questions about the dipeptidyl peptidase (DPP)-4 inhibitor sitagliptin (Januvia, Merck)….

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Avatar of Richard Lehman, BM, BCh, MRCGP

Selections from Richard Lehman’s Literature Review: June 30th (30 Jun 2014)

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Richard Lehman, BM, BCh, MRCGP

This week’s topics include atrial fibrillation and cryptogenic stroke, higher potency statins and the risk for new diabetes, and more.

Avatar of Physician's First Watch, CardioExchange Staff

To Screen or Not for AF: Is That the Question? (26 Jun 2014)

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Up to one third of ischemic strokes are of uncertain etiology or “cryptogenic,” meaning that there is no overt explanation such as severe carotid stenosis, intracranial stenosis, or documented atrial fibrillation (AF). For some of these patients, intermittent AF may be present and could explain the ischemic stroke. This issue has been addressed by two…

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