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Selections from Richard Lehman’s Literature Review: April 9th (9 Apr 2015)

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Richard Lehman, BM, BCh, MRCGP

This week’s topics include the PROMISE trial, the efficacy of folic acid therapy in primary prevention of stroke among patients with hypertension in China, and more.

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Association Between Shorter Height and Heart Disease Largely Explained by Genes (9 Apr 2015)

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The “well-established” link between shorter adult height and increased risk for coronary artery disease (CAD) is largely explained by height-associated genetic variants, researchers conclude in the New England Journal of Medicine. Using data from genome-wide association studies, the researchers examined the relationship between 180 height-associated genetic variants and CAD among 65,000 cases (adults with histories…

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Weight-Loss Programs: Slim Evidence and Thin Results (6 Apr 2015)

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A new study concludes that some weight-loss programs may be slightly better than other programs but that in the long run none of the programs have been able to show a substantial weight loss over a sustained period. For even the best programs, an editorialist writes, “weight loss is modest and likely below patients’ expectations.”…

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Cardiac Arrest During Exercise in Middle-Aged People (6 Apr 2015)

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Dropping dead while exercising is a common fear, especially among middle-aged men. Unfortunately there have been limited data on the precise rate of sudden cardiac arrest (SCA) in middle-aged people and little understanding about the medical history of the victims of SCA. Now a new study fills in some important gaps in knowledge and shows that this…

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Bringing Clarity and Consensus to the Treatment of Hypertension in Patients with CAD (6 Apr 2015)

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Elliott Antman, MD

AHA President Elliott Antman discusses the recent scientific statement from the AHA/ACC/ASH on the treatment of hypertension in patients with existing CAD.

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Liberal Changes to rt-PA Contraindications for Acute Ischemic Stroke (2 Apr 2015)

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Craig Cocchio, PharmD, BCPS

Dr. Craig Cocchio discussing changes to the contraindications for acute ischemic stroke, about which the FDA has been curiously silent.

Avatar of Larry Husten, PHD

Global Cardiovascular Deaths Continue to Rise Despite Gains in Prevention and Treatment (2 Apr 2015)

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Improvements in the treatment and prevention of cardiovascular disease haven’t been able to prevent a worldwide rise in cardiovascular deaths in a growing and aging population, according to the authors of a paper published in the New England Journal of Medicine. Using mortality data from the Global Burden of Disease Study 2013, the authors set out to “disentangle”…

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Selections from Richard Lehman’s Literature Review: March 30th (30 Mar 2015)

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Richard Lehman, BM, BCh, MRCGP

This week’s topics include two papers comparing everolimus-eluting stents and CABG and a study of short-term exposure to air pollution and stroke.

Avatar of Larry Husten, PHD

How Do You Like Them Apples? (30 Mar 2015)

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An apple a day does not appear to keep the doctor away but, a new study semi-seriously suggests, it may keep the pharmacist away. Although apples have long been considered a healthy snack, whether eating apples actually reduces healthcare use has not been assessed until now. In a paper published in JAMA Internal Medicine researchers…

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Fighting the Contradiction: A Hospital Rolls Out the Red Carpet for Smokers (27 Mar 2015)

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Jean-Pierre Usdin, MD

Jean-Pierre Usdin is frustrated with his “Tobacco-Free” hospital’s accommodations for smokers that encourage them to keep smoking instead of supporting them to quit.