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Another Diet Myth Exploded: Gradual Weight Loss No Better Than Rapid Weight Loss (15 Oct 2014)

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Once again, a popular weight loss myth has been exploded. It has been widely believed that weight loss, which is nearly always difficult to maintain, is even less likely to be sustained if it’s the product of a rapid weight-loss regimen. This belief is even enshrined in current guidelines. Now a study published in The…

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Inappropriate Cardiac Stress Tests May Cost Half a Billion Dollars a Year (14 Oct 2014)

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Inappropriate cardiac stress tests may cost the U.S. healthcare system as much as half a billion dollars each year, according to a new study published in the Annals of Internal Medicine. Joseph Ladapo and colleagues set out to analyze long-term trends in the use of cardiac stress testing in the U.S. Using data from national surveys, they…

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Medicare Reimbursement for Lung Cancer Screening Provokes Debate (13 Oct 2014)

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Although 160,000 people in the U.S. die each year from lung cancer, accounting for more than a quarter of all cancer deaths, screening for lung cancer remains controversial. Based on results from the National Lung Screening Trial (NLST) in 2011, the U.S. Preventive Services Task Force (USPSTF) issued a B recommendation in favor of low-dose…

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Selections from Richard Lehman’s Literature Review: October 13th (13 Oct 2014)

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Richard Lehman, BM, BCh, MRCGP

This week’s topics include a comparison of once-weekly dulaglutide and once-daily liraglutide in metformin-treated patients with type 2 diabetes and variation in patients’ perceptions of elective PCI in stable CAD.

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First Drug-Coated Balloon Approved by FDA for Leg Blockages (13 Oct 2014)

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The FDA today announced that it had approved for use in the U.S. the first drug-coated angioplasty balloon catheter to re-open blocked arteries in the superficial femoral and popliteal arteries. The Lutonix 035 Drug Coated Balloon Percutaneous Transluminal Angioplasty Catheter (Lutonix DCB) is manufactured by CR Bard and has been available in Europe since 2012. “Peripheral artery disease can be quite serious….

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Why Bad Doctors Are Like Bad Writers: The Curse Of Knowledge (9 Oct 2014)

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Larry Husten, PhD

Larry Husten applies Steven Pinker’s ideas about the difficulties of writing to the field of medicine by looking at what makes it difficult for doctors to communicate with their patients.

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FDA Panel Gives Cautious Endorsement to Novel Boston Scientific Device (9 Oct 2014)

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The FDA’s Circulatory System Devices advisory panel gave an extremely cautious endorsement on Wednesday to Boston Scientific’s Watchman device, a novel catheter-delivered left atrial appendage closure device for people with atrial fibrillation. They signaled that although they thought the device should be made available they also thought that there should be significant restrictions on its use. The panel wrestled…

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Another Reason for Open Access to Clinical Trial Data? (7 Oct 2014)

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Harlan M. Krumholz, MD, SM

A correction to the RE-LY trial results, partly brought to light because of litigation, has Harlan Krumholz wondering if this is another example of why we should have open access to clinical trial data.

Avatar of Richard Lehman, BM, BCh, MRCGP

Selections from Richard Lehman’s Literature Review: October 6th (6 Oct 2014)

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Richard Lehman, BM, BCh, MRCGP

This week’s topics include medical device safety and effectiveness, familial hypercholesterolemia, and more.

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Nissen Urges Prompt Revision of Cardiovascular Guidelines (6 Oct 2014)

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Sparked by a new study that once again finds serious flaws in the cardiovascular risk calculator at the heart of the American College of Cardiology/American Heart Association cardiovascular guidelines, Steve Nissen states that “the ACC and AHA should promptly revise the guidelines to address the criticisms offered by independent authorities.” The CV risk calculator is a…

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