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Good Night, and Good Luck (15 May 2015)

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CardioExchange Editors, Staff

A final farewell from the CardioExchange editors

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Get a Grip: Global Study Finds Grip Strength Is a Simple and Powerful Predictor Of Death (13 May 2015)

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A large global study finds that grip strength is a simple, powerful, and broadly applicable test that can help predict the risk of death and cardiovascular disease. The new findings from the Prospective Urban-Rural Epidemiology (PURE) study were based on data from nearly 140,000 adults in 17 countries. The study participants had their grip strength…

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Diet Drug Study Crashes and Burns in the Wake of Leaked Results (12 May 2015)

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The ill-fated Light trial, which was supposed to examine the cardiovascular outcomes of the weight loss drug Contrave, a combination of naltrexone and bupropion marketed by Orexigen and Takeda, came to a spectacular halt today. The action was probably inevitable given the extreme controversy generated earlier this year when it became known that Orexigen had widely disseminated results from an early…

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Selections from Richard Lehman’s Literature Review: May 11th (11 May 2015)

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Richard Lehman, BM, BCh, MRCGP

This week’s topics include a comparison of catheter ablation for persistent AF, left atrial appendage exclusion with the Lariat device, the obesity paradox in type 2 diabetes, and more.

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Prominent Harvard Cardiologist Moves to Google X to Head Large Study (11 May 2015)

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Here’s a clear sign of the ascending role of digital/precision/personalized medicine: a prominent cardiologist has left a top academic and clinical position in Boston to run a large, innovative study in Silicon Valley. Jessica Mega was widely perceived as a rising star at Harvard Medical School and the Brigham and Women’s Hospital. She has now joined Google X, Google’s research arm,…

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Big Data, Big Problems (7 May 2015)

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John Ryan, MD

Calling attention to the health data generated by today’s wearable devices, John Ryan wonders: Who ultimately owns this information and what can they do with it?

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Selections from Richard Lehman’s Literature Review: May 7th (7 May 2015)

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Richard Lehman, BM, BCh, MRCGP

This week’s topics are a comparison of a retrievable inferior vena cava filter plus anticoagulation vs. anticogulation alone for recurrent PE, the cost effectiveness and population impact of statins for primary prevention in U.S. adults age 75 and older, and more.

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Advocates Say Precision Medicine Could Lead to Enormous Benefits (7 May 2015)

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Personalized and precision medicine (PPM) could deliver hundreds of billions of dollars worth of improved health in the next 50 years in the United States, writes Victor Dzau, the new president of the Institute of Medicine, and coauthors in a Viewpoint published in the Lancet. The authors used a health simulation model to estimate the effect…

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A Message from the Editor-in-Chief (1 May 2015)

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Harlan M. Krumholz, MD, SM

Harlan Krumholz reflects on the CardioExchange community.

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A Message from NEJM Group (1 May 2015)

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Jonathan N. Adler, MD, MS

An important notification about CardioExchange