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Avatar of Larry Husten, PHD

FDA Approves New Noninvasive FFR Technology (28 Nov 2014)

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The FDA said Wednesday that it had granted approval to a novel technology that noninvasively measures fractional flow reserve (FFR) using data obtained from a CT scan of the heart. In recent years a catheter-based form of FFR has been used by interventional cardiologists during catheterization procedures to measure the pressure gradient in partially blocked…

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Avatar of Brahmajee Kartik Nallamothu, MD, MPH

Resolving the Questions About Door-to-Balloon Times (26 Nov 2014)

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Brahmajee Kartik Nallamothu, MD, MPH

Brahmajee K. Nallamothu discusses his research group’s retrospective study of changes, over time, in the relation between door-to-balloon times and mortality after primary PCI.

Avatar of Larry Husten, PHD

Prolonged Dual Antiplatelet Therapy Affirmed in DAPT (16 Nov 2014)

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The advent of drug-eluting stents dramatically reduced the restenosis rate associated with bare-metal stents but prompted new concerns about the rare but potentially lethal complication of stent thrombosis (ST). Cardiologists have relied upon dual antiplatelet therapy to prevent ST but there has been considerable uncertainty and controversy about the ideal duration of therapy. The Dual…

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Avatar of Larry Husten, PHD

Aortic Valve Surgery for Nonagenarians (30 Oct 2014)

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As people continue to live longer physicians are increasingly confronted with very elderly patients who have serious conditions that might benefit from surgery but who are at high risk for surgical complications. In a paper published in the Annals of Thoracic Surgery, doctors at the Mayo Clinic reviewed their experience with 59 patients age 90 or…

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Avatar of Larry Husten, PHD

First Drug-Coated Balloon Approved by FDA for Leg Blockages (13 Oct 2014)

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The FDA today announced that it had approved for use in the U.S. the first drug-coated angioplasty balloon catheter to re-open blocked arteries in the superficial femoral and popliteal arteries. The Lutonix 035 Drug Coated Balloon Percutaneous Transluminal Angioplasty Catheter (Lutonix DCB) is manufactured by CR Bard and has been available in Europe since 2012. “Peripheral artery disease can be quite serious….

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Avatar of Larry Husten, PHD

FDA Panel Gives Cautious Endorsement to Novel Boston Scientific Device (9 Oct 2014)

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The FDA’s Circulatory System Devices advisory panel gave an extremely cautious endorsement on Wednesday to Boston Scientific’s Watchman device, a novel catheter-delivered left atrial appendage closure device for people with atrial fibrillation. They signaled that although they thought the device should be made available they also thought that there should be significant restrictions on its use. The panel wrestled…

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Avatar of Seth

Case: Testosterone Replacement Therapy and CV Risk (1 Oct 2014)

Cardiology Case Discussion

Seth D Bilazarian, MD, Anna Catino, MD, and James Fang, MD

A 47-year-old man presents to the hospital reporting 4 days of chest pain that occurs during treadmill exercise, left-arm and jaw discomfort, and shortness of breath with diaphoresis. His medical history is noteworthy only for orthopedic surgeries and use of testosterone replacement therapy for reportedly low testosterone syndrome. He does not smoke and drinks alcohol only…

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ACC and AHA Release New Guideline for Non–ST-Elevation Acute Coronary Syndromes (23 Sep 2014)

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A new guideline released today by the American College of Cardiology and the American Heart Association reflects important changes in the last 7 years in the understanding of what is now known as non–ST-elevation acute coronary syndromes (NSTE-ACS). The previous 2007 guideline used different terminology and referred to the same patient population as “unstable angina…

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Avatar of Larry Husten, PHD

ACC Withdraws ‘Choosing Wisely’ Recommendation Against Revascularization of Nonculprit Lesions (22 Sep 2014)

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The American College of Cardiology said today that it was withdrawing one of its five recommendations in the “Choosing Wisely” campaign.  In 2012 the ACC recommended that heart attack patients should have only their culprit artery unblocked. It said that patients and caregivers should question whether complete revascularization of all nonculprit lesions in heart attack…

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Is It Safe to Offer PCI at VA Centers Without On-Site Cardiothoracic Surgery? (17 Sep 2014)

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Thomas Maddox, MD MSc

Thomas M. Maddox discusses his research group’s study of post-PCI outcomes at VA centers with or without on-site cardiothoracic surgery.