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First Drug-Coated Balloon Approved by FDA for Leg Blockages (13 Oct 2014)

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The FDA today announced that it had approved for use in the U.S. the first drug-coated angioplasty balloon catheter to re-open blocked arteries in the superficial femoral and popliteal arteries. The Lutonix 035 Drug Coated Balloon Percutaneous Transluminal Angioplasty Catheter (Lutonix DCB) is manufactured by CR Bard and has been available in Europe since 2012. “Peripheral artery disease can be quite serious….

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FDA Panel Gives Cautious Endorsement to Novel Boston Scientific Device (9 Oct 2014)

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The FDA’s Circulatory System Devices advisory panel gave an extremely cautious endorsement on Wednesday to Boston Scientific’s Watchman device, a novel catheter-delivered left atrial appendage closure device for people with atrial fibrillation. They signaled that although they thought the device should be made available they also thought that there should be significant restrictions on its use. The panel wrestled…

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Case: Testosterone Replacement Therapy and CV Risk (1 Oct 2014)

Cardiology Case Discussion

Seth D Bilazarian, MD, Anna Catino, MD, and James Fang, MD

A 47-year-old man presents to the hospital reporting 4 days of chest pain that occurs during treadmill exercise, left-arm and jaw discomfort, and shortness of breath with diaphoresis. His medical history is noteworthy only for orthopedic surgeries and use of testosterone replacement therapy for reportedly low testosterone syndrome. He does not smoke and drinks alcohol only…

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ACC and AHA Release New Guideline for Non–ST-Elevation Acute Coronary Syndromes (23 Sep 2014)

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A new guideline released today by the American College of Cardiology and the American Heart Association reflects important changes in the last 7 years in the understanding of what is now known as non–ST-elevation acute coronary syndromes (NSTE-ACS). The previous 2007 guideline used different terminology and referred to the same patient population as “unstable angina…

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ACC Withdraws ‘Choosing Wisely’ Recommendation Against Revascularization of Nonculprit Lesions (22 Sep 2014)

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The American College of Cardiology said today that it was withdrawing one of its five recommendations in the “Choosing Wisely” campaign.  In 2012 the ACC recommended that heart attack patients should have only their culprit artery unblocked. It said that patients and caregivers should question whether complete revascularization of all nonculprit lesions in heart attack…

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Is It Safe to Offer PCI at VA Centers Without On-Site Cardiothoracic Surgery? (17 Sep 2014)

Voices

Thomas Maddox, MD MSc

Thomas M. Maddox discusses his research group’s study of post-PCI outcomes at VA centers with or without on-site cardiothoracic surgery.

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Anteroseptal MI and Left-Main Dissection in a Pregnant Woman (8 Sep 2014)

Cardiology Case Discussion

Harsh Golwala, MD and James Fang, MD

Harsh Golwala presents our latest case: A 25-year-old woman, 32 weeks pregnant, presents with sudden-onset chest pain. How do you proceed?

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FAME 2 at 2 Years: Better with Time? (3 Sep 2014)

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CardioExchange Editors, Staff

The CardioExchange editors ask whether the 2-year findings from FAME 2 are more compelling than the 7-month findings.

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Fractional Flow Reserve Gains Support in Stable CAD and NSTEMI (2 Sep 2014)

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Two studies presented at the European Society of Cardiology meeting in Barcelona offered fresh support for fractional flow reserve (FFR), which has been slowly but surely gaining traction in the interventional cardiology community. FFR in Patients with Stable CAD Bernard De Bruyne presented 2-year results from the FAME 2 (Fractional flow reserve versus Angiography for…

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New Support For Complete Revascularization During Primary PCI (1 Sep 2014)

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Until recently, MI patients receiving emergency PCI would only have the culprit artery opened. Complete revascularization of non-infarct-related arteries was performed later. The conventional wisdom was that revascularization of non-infarct-related arteries could be dangerous. That wisdom began to change last year with the PRAMI trial, which found no evidence of harm and a suggestion of benefit in…

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