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Anteroseptal MI and Left-Main Dissection in a Pregnant Woman (8 Sep 2014)

Cardiology Case Discussion

Harsh Golwala, MD

Harsh Golwala presents our latest case: A 25-year-old woman, 32 weeks pregnant, presents with sudden-onset chest pain. How do you proceed?

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FAME 2 at 2 Years: Better with Time? (3 Sep 2014)

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CardioExchange Editors, Staff

The CardioExchange editors ask whether the 2-year findings from FAME 2 are more compelling than the 7-month findings.

Avatar of Larry Husten, PHD

Fractional Flow Reserve Gains Support in Stable CAD and NSTEMI (2 Sep 2014)

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Two studies presented at the European Society of Cardiology meeting in Barcelona offered fresh support for fractional flow reserve (FFR), which has been slowly but surely gaining traction in the interventional cardiology community. FFR in Patients with Stable CAD Bernard De Bruyne presented 2-year results from the FAME 2 (Fractional flow reserve versus Angiography for…

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Avatar of Larry Husten, PHD

New Support For Complete Revascularization During Primary PCI (1 Sep 2014)

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Until recently, MI patients receiving emergency PCI would only have the culprit artery opened. Complete revascularization of non-infarct-related arteries was performed later. The conventional wisdom was that revascularization of non-infarct-related arteries could be dangerous. That wisdom began to change last year with the PRAMI trial, which found no evidence of harm and a suggestion of benefit in…

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Radial Access for PCI in Women: A Registry-Based Randomized Trial (18 Aug 2014)

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Sunil Rao, MD, Harlan M. Krumholz, MD, SM, and John Ryan, MD

Harlan Krumholz and John Ryan interview Sunil Rao, lead author of SAFE-PCI for Women, a registry-based randomized trial of a radial versus a femoral approach to PCI.

Avatar of Larry Husten, PHD

Large Analysis Supports Thrombolysis for Stroke (5 Aug 2014)

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Although thrombolysis for ischemic stroke has been widely recognized as beneficial, its use has been limited because of concerns about its effects in patients treated after 3 hours, in older patients, and in patients with mild and with severe strokes. Now a meta-analysis published in the Lancet offers evidence that the use of thrombolysis should be…

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Can Bivalirudin Stand the HEAT? (14 Jul 2014)

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Peter B Berger, MD

Harlan Krumholz interviews Peter Berger, an editorialist for the HEAT-PPCI study, about the paper’s findings.

Avatar of Richard A. Lange, MD, MBA

Do FFR and IVUS Feed the Elephant? (11 Jul 2014)

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Richard A. Lange, MD, MBA and L. David Hillis, MD

Rick Lange and David Hillis wonder whether the debate about the role of FFR and IVUS in patient selection for PCI is a red herring in the larger issue of revascularization in patients with stable CAD.

Avatar of Larry Husten, PHD

HEAT-PPCI: Heparin Beats Bivalirudin in Primary PCI (7 Jul 2014)

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Although there is broad consensus in the medical community that primary PCI is the best treatment for MI patients when it can be delivered promptly, there is no agreement about the best accompanying drug regimen, which usually entails a combination of antiplatelet and antithrombotic drugs. The role of one antithrombotic, bivalirudin (Angiomax, The Medicines Company) has…

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Avatar of Larry Husten, PHD

Registry Study Offers Reassurance About Newer Drug-Eluting Stents (30 Jun 2014)

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Findings from a large ongoing registry study provide some reassurance about the long-term safety of new-generation drug-eluting stents (DES)  in patients with STEMI who undergo primary PCI. The results are published online in the Journal of the American College of Cardiology. SCAAR (Swedish Coronary Angiography and Angioplasty Registry) investigators analyzed data from 34,000 primary PCI patients…

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