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FDA Approves New Drug-Coated Balloon to Open Blocked Leg Arteries (5 Jan 2015)

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Medtronic said today that it had received approval from the FDA to market its IN.PACT Admiral drug-coated balloon (DCB) to treat peripheral artery disease (PAD) in the superficial femoral and popliteal arteries. The device is the second DCB to gain FDA approval. Last October the FDA approved CR Bard’s Lutonix DCB for a similar indication. The new DCB uses the anti-proliferative drug…

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An Examination of MR CLEAN (24 Dec 2014)

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Rory J Spiegel, MD

Rory Spiegel examines why the MR CLEAN trial of interventional therapy for acute ischemic stroke succeeded where its predecessors failed.

Avatar of Larry Husten, PHD

Dutch Trial Gives Support to Thrombectomy for Ischemic Stroke (17 Dec 2014)

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A large new trial provides the first substantial evidence that thrombectomy may be beneficial in patients with acute ischemic stroke. Previous thromboectomy trials have been disappointing; some experts have speculated this may be due to the use of early-generation devices, long treatment delays, and difficulties in recruiting suitable patients into the trials. The Multicenter Randomized…

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The Latest on Culprit-Vessel vs. Multivessel Primary PCI for STEMI (15 Dec 2014)

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Bilal Iqbal, MBBS MRCP PhD and CardioExchange Editors, Staff

We interview Bilal Iqbal about his real-world observational analysis of culprit-vessel vs. multivessel intervention at the time of primary PCI for STEMI.

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Triple-Vessel Disease in an Asymptomatic Man: CABG, PCI, or Medical Management? (11 Dec 2014)

Cardiology Case Discussion

Amit Shah, MD, MSCR and James Fang, MD

Amit Shah presents the case of a 66-year-old, physically active, nondiabetic man with no symptoms who was tested for coronary artery calcium and received an unexpectedly high score.

Avatar of Larry Husten, PHD

FDA Approves New Noninvasive FFR Technology (28 Nov 2014)

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The FDA said Wednesday that it had granted approval to a novel technology that noninvasively measures fractional flow reserve (FFR) using data obtained from a CT scan of the heart. In recent years a catheter-based form of FFR has been used by interventional cardiologists during catheterization procedures to measure the pressure gradient in partially blocked…

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Avatar of Brahmajee Kartik Nallamothu, MD, MPH

Resolving the Questions About Door-to-Balloon Times (26 Nov 2014)

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Brahmajee Kartik Nallamothu, MD, MPH

Brahmajee K. Nallamothu discusses his research group’s retrospective study of changes, over time, in the relation between door-to-balloon times and mortality after primary PCI.

Avatar of Larry Husten, PHD

Prolonged Dual Antiplatelet Therapy Affirmed in DAPT (16 Nov 2014)

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The advent of drug-eluting stents dramatically reduced the restenosis rate associated with bare-metal stents but prompted new concerns about the rare but potentially lethal complication of stent thrombosis (ST). Cardiologists have relied upon dual antiplatelet therapy to prevent ST but there has been considerable uncertainty and controversy about the ideal duration of therapy. The Dual…

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Avatar of Larry Husten, PHD

Aortic Valve Surgery for Nonagenarians (30 Oct 2014)

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As people continue to live longer physicians are increasingly confronted with very elderly patients who have serious conditions that might benefit from surgery but who are at high risk for surgical complications. In a paper published in the Annals of Thoracic Surgery, doctors at the Mayo Clinic reviewed their experience with 59 patients age 90 or…

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Avatar of Larry Husten, PHD

First Drug-Coated Balloon Approved by FDA for Leg Blockages (13 Oct 2014)

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The FDA today announced that it had approved for use in the U.S. the first drug-coated angioplasty balloon catheter to re-open blocked arteries in the superficial femoral and popliteal arteries. The Lutonix 035 Drug Coated Balloon Percutaneous Transluminal Angioplasty Catheter (Lutonix DCB) is manufactured by CR Bard and has been available in Europe since 2012. “Peripheral artery disease can be quite serious….

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