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Avatar of Larry Husten, PHD

Another Diet Myth Exploded: Gradual Weight Loss No Better Than Rapid Weight Loss (15 Oct 2014)

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Once again, a popular weight loss myth has been exploded. It has been widely believed that weight loss, which is nearly always difficult to maintain, is even less likely to be sustained if it’s the product of a rapid weight-loss regimen. This belief is even enshrined in current guidelines. Now a study published in The…

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Avatar of Larry Husten, PHD

Inappropriate Cardiac Stress Tests May Cost Half a Billion Dollars a Year (14 Oct 2014)

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Inappropriate cardiac stress tests may cost the U.S. healthcare system as much as half a billion dollars each year, according to a new study published in the Annals of Internal Medicine. Joseph Ladapo and colleagues set out to analyze long-term trends in the use of cardiac stress testing in the U.S. Using data from national surveys, they…

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Avatar of Larry Husten, PHD

Medicare Reimbursement for Lung Cancer Screening Provokes Debate (13 Oct 2014)

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Although 160,000 people in the U.S. die each year from lung cancer, accounting for more than a quarter of all cancer deaths, screening for lung cancer remains controversial. Based on results from the National Lung Screening Trial (NLST) in 2011, the U.S. Preventive Services Task Force (USPSTF) issued a B recommendation in favor of low-dose…

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Avatar of Larry Husten, PHD

Nissen Urges Prompt Revision of Cardiovascular Guidelines (6 Oct 2014)

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Sparked by a new study that once again finds serious flaws in the cardiovascular risk calculator at the heart of the American College of Cardiology/American Heart Association cardiovascular guidelines, Steve Nissen states that “the ACC and AHA should promptly revise the guidelines to address the criticisms offered by independent authorities.” The CV risk calculator is a…

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Case: Testosterone Replacement Therapy and CV Risk (1 Oct 2014)

Cardiology Case Discussion

Seth D Bilazarian, MD, Anna Catino, MD, and James Fang, MD

A 47-year-old man presents to the hospital reporting 4 days of chest pain that occurs during treadmill exercise, left-arm and jaw discomfort, and shortness of breath with diaphoresis. His medical history is noteworthy only for orthopedic surgeries and use of testosterone replacement therapy for reportedly low testosterone syndrome. He does not smoke and drinks alcohol only…

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Avatar of Larry Husten, PHD

Genetic Analysis Fails to Support Vitamin D to Prevent Diabetes (30 Sep 2014)

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A vitamin D pill can’t substitute for a healthy diet and sunshine, a new genetic study published in The Lancet Diabetes & Endocrinology suggests. In recent years many people have been seduced by observational studies that found low levels of vitamin D in people who developed type 2 diabetes. The new study instead suggests that the association…

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Avatar of Larry Husten, PHD

FDA Approves New Once-Weekly GLP-1 Receptor Agonist for Type 2 Diabetes (18 Sep 2014)

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The FDA said today that it had approved dulaglutide, Lilly’s once-weekly injection to control blood sugar in adults with type 2 diabetes. The drug will be marketed under the brand name of Trulicity. The FDA said that the safety and efficacy of dulaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, had been studied in  3,342 type 2 diabetics. The…

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Avatar of Larry Husten, PHD

Cheaper Generic Statins Beat Brand-Name Statins in Adherence and Outcomes (15 Sep 2014)

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A large observational study finds that people who received a prescription for a generic statin were more likely to take their pills than people who received a prescription for a brand-name statin. This increased adherence appeared to lead to a small but significant improvement in outcomes. In a paper published in Annals of Internal Medicine, Joshua…

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No Endorsement for Routine ECG Screening of Young People (15 Sep 2014)

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In a new scientific statement the American Heart Association and the American College of Cardiology do not recommend the routine initial use of ECGs to screen young people for underlying congenital or genetic heart disease. More aggressive screening for heart disease in young people is often advocated in response to pressure resulting from the rare…

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Avatar of Benjamin Scirica, MD MPH

New Observations on Saxagliptin (15 Sep 2014)

Voices

Benjamin Scirica, MD MPH

Benjamin Scirica discusses his study group’s new analysis of data from the SAVOR-TIMI 53 randomized, placebo-controlled trial of saxagliptin in patients with type 2 diabetes.