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Avatar of Larry Husten, PHD

Lower Rate of Microvascular Complications in Statin Users Who Develop Diabetes (9 Sep 2014)

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In recent years, the medical community has become increasingly aware that taking statins can result in slightly higher glucose levels, and this can lead to a diagnosis of diabetes in a small but statistically significant number of people. But it has been unclear whether the diagnosis of diabetes in people taking statins also places them…

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FDA: Risk for Venous Thromboembolism with All Testosterone Products (23 Jun 2014)

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The FDA is requiring an expanded label change to all approved testosterone products to warn of the increased risk for venous thromboembolism. Labels currently address the risk for clots associated with polycythemia caused by testosterone treatment. The action follows reports of blood clots in testosterone users unrelated to polycythemia. The agency says the warning is…

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Vena Cava Filters Reduce Pulmonary Emboli But Increase VTE Recurrence Tenfold (6 Mar 2014)

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Inferior vena cava filters seem to offer protection against death from pulmonary embolism when compared with anticoagulant therapy, but they have no significant effect on all-cause mortality. In addition, the filters are associated with higher rates of recurrent venous thromboembolism, according to an article in the Journal of the American College of Cardiology. Researchers examined…

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Avatar of Larry Husten, PHD

Stent Remains Available Despite Trial Showing Dangers (24 Jan 2014)

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A leading critic says that the FDA has been remiss for not removing a stent from the market although strong evidence exists that its use leads to more deaths and strokes. The Wingspan intracranial stent, manufactured by Stryker Neurovascular, was approved in 2005 by the FDA through the humanitarian device exemption (HDE) for the rare…

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Nontechnical Skills Matter in the Cardiac Operating Room (9 Sep 2013)

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Joyce Ann Wahr, M.D. and Harlan M. Krumholz, MD, SM

Joyce A. Wahr discusses the importance of teamwork and communication in performing cardiac surgery, as described in a new AHA scientific statement.

Avatar of Larry Husten, PHD

American Heart Association Announces Late-Breaking Clinical Trials (28 Aug 2013)

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There are still a few days left in August, and the European Society of Cardiology meeting doesn’t start until this weekend in Amsterdam. Nevertheless, the American Heart Association has released the list of late-breaking clinical trials for its annual meeting in November. Late-Breaking Clinical Trials 1: Acute Cardiovascular and Cerebrovascular Care Sunday, Nov 17, 2013, 4:00 PM –…

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How Do Patients with CAD Fare After TAVR? (3 Jun 2013)

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Sachin Goel, MD and Erica Sarah Spatz, MD, MHS

Sachin Goel discusses his research group’s literature review focusing on patients with coronary artery disease who are evaluated for — and those who undergo — transcatheter aortic valve replacement.

Avatar of Behnood Bikdeli, M.D.

Should the Use of IVC Filters be Filtered Until We Have More Data? (26 Mar 2013)

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Behnood Bikdeli, M.D.

There’s been a remarkable increase in the use of IVC filters, but what is the evidence base behind this mechanistically appealing approach?

Avatar of Larry Husten, PHD

HPS2-THRIVE Coming Attraction: What Went Wrong with Niacin? (27 Feb 2013)

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In less than two weeks, on March 9, the main results of the HPS2-THRIVE (Heart Protection Study 2-Treatment of HDL to Reduce the Incidence of Vascular Events) study will be presented in San Francisco at the annual meeting of the American College of Cardiology. The results have been eagerly awaited since Merck’s brief announcement in December that the trial had not met its primary endpoint and that it…

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ACE Inhibitor Improves Walking in People with Peripheral Artery Disease (5 Feb 2013)

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Giving an ACE inhibitor to people with peripheral artery disease (PAD) and intermittent claudication reduces pain and increases walking time, according to a new study published in JAMA. Currently the pharmacologic options for this patient population are few and have limited efficacy. Researchers at three Australian hospitals randomized 212 patients with PAD to receive the ACE inhibitor ramipril or placebo for…

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