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Archives for April 2012

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Engage with independent insights, opinions, and analysis from an array of leaders in cardiology.
Avatar of Richard Lehman, BM, BCh, MRCGP

Selections from Richard Lehman’s Literature Review: Week of April 30th (30 Apr 2012)

Richard Lehman, BM, BCh, MRCGP

This week, Richard looks at endocarditis and ICDs, more stent wars, stroke prevention in A-Fib, and more.

Avatar of John

Frailty Evaluation and High-Risk Interventions (26 Apr 2012)

John A. Dodson, MD

When taking care of older patients, we often have an intuitive sense of which ones will do well after an intervention and which ones won’t. This has been termed the “foot of the bed” test, or alternately something which separates a “young 80-year old” from an “old 80-year old.”  Frailty is a syndrome defined as an increased physiologic vulnerability to stressors, and through its quantification we can help to standardize this clinical intuition. However, the routine measurement of frailty has largely remained outside both clinical trials and patient care. A… Continue Reading

Avatar of Richard Lehman, BM, BCh, MRCGP

Selections from Richard Lehman’s Literature Review: Week of April 23rd (23 Apr 2012)

Richard Lehman, BM, BCh, MRCGP

This week, Richard discusses JAMA’s coverage of patient-centered care and all things CABG in NEJM.

Avatar of Richard Lehman, BM, BCh, MRCGP

Selections from Richard Lehman’s Literature Review: Week of April 16th (18 Apr 2012)

Richard Lehman, BM, BCh, MRCGP

This week’s topics include an “awful question” about statin therapy, coronary computed tomographic angiography in the ED, vorapraxar for secondary prevention, and stent wars.

Avatar of Nicholas

What’s in a Name? Go for the Generic (17 Apr 2012)

Nicholas Downing, MD

A recent report published in the Archives of Internal Medicine highlights some “low-hanging fruit” for anyone trying to deliver more cost-effective healthcare. The authors (I am the first author and Harlan Krumholz, CardioExchange editor-in-chief, is the senior author) describe how branded formulations of fenofibrate — marketed by Abbott as Tricor and Trilipix — account for the vast majority of fenofibrate prescriptions, even though generic fenofibrate has been available for almost a decade. Abbott was able to stay one step ahead of the generic competition by repeatedly changing the dose of its branded formulations:… Continue Reading

Avatar of Westby G Fisher, MD

The Audible (16 Apr 2012)

Westby G Fisher, MD

Every electrophysiologist knows there are a million things that can be done for patients with atrial fibrillation. But sometimes not doing an invasive procedure is the best choice.

Avatar of Lisa Rosenbaum, MD

CT Angiography for Safe Discharge of Patients (13 Apr 2012)

Lisa Rosenbaum, MD

(Reprinted with permission from NOW@NEJM, a blog for physicians about the New England Journal of Medicine) Chest pain is the second most common reason for Emergency Room visits in this country, and although only 10-15% of patients admitted with chest pain are ultimately diagnosed with an acute coronary syndrome, the majority of patients get admitted. So common, in fact, is this admission diagnosis, that during cardiology rounds the other week, when I asked a resident how the patient was doing, she responded, “Oh fine, we’re just rome-eee-ing him,” (a new… Continue Reading

Avatar of Edward McNulty, MD

Ascertaining ASCERT: How Well Do Registry Data Measure Up to the ‘Bedside Test’? (12 Apr 2012)

Edward McNulty, MD

In the ASCERT observational study, stable patients (age 65 or older) with double- or triple-vessel CAD, but not left-main disease, were found to have better long-term survival after CABG than after PCI. ASCERT was a laudable achievement in terms of its scope and the level of collaboration it represents. The ASCERT investigators used inverse probability weighting (propensity scores) in an attempt to mitigate the impact of selection bias. However, this technique depends on measured variables. Experts are currently debating whether the registries analyzed in ASCERT — the STS Adult Cardiac Surgery… Continue Reading

Avatar of Richard Lehman, BM, BCh, MRCGP

Selections from Richard Lehman’s Literature Review: Week of April 10th (10 Apr 2012)

Richard Lehman, BM, BCh, MRCGP

This week’s topics include the EINSTEIN-PE trial of rivaroxaban, the risk for suicide or cardiovascular death after cancer diagnosis, and a comparison of computer reminders vs. pharmacist outreach about medication dangers.

Avatar of Westby G Fisher, MD

David vs. Goliath: St. Jude Medical Seeks Retraction of Heart Rhythm Journal Manuscript (9 Apr 2012)

Westby G Fisher, MD

CardioExchange welcomes this guest post from Dr. Westby Fisher, an electrophysiologist practicing at NorthShore University HealthSystem in Evanston, Illinois, and a Clinical Associate Professor of Medicine at University of Chicago’s Pritzker School of Medicine. This piece originally appeared on his blog, Dr. Wes. St. Jude Medical, a widely-used manufacturer of implantable cardiac devices, finds they have a bit of a problem with a form of insulation that surrounds wires contained in several lines of their pacing and defibrillator leads. They decide to pull these products from the market after substantial evidence that their leads’ reliability… Continue Reading